Healthcare CDSS Patterns

• You are building or extending a medication order entry system and need drug interaction and dose safety checks.
• You need to implement clinical early warning scoring (NEWS2, qSOFA) tied to escalation workflows.
• Your team needs a reference architecture for CDSS that is fully testable and auditable.
• You are integrating safety alerts into an EMR UI and need guidance on alert severity, UI behavior, and override audit logging.

• You need a ready-to-deploy drug interaction database — this skill provides patterns and interfaces, not the underlying drug data source.
• Your project is outside clinical/healthcare software and does not require patient safety constraints.
• You are looking for a no-code or low-code solution; these patterns require TypeScript/programming implementation.

The checkInteractions function checks a new drug against all current medications and the patient's allergy list, returning severity-sorted alerts. Interaction pairs are enforced as bidirectional, and cross-reactive allergies always produce critical-severity blocks.

The validateDose function enforces weight-based (mg/kg), age-adjusted, renal-adjusted, and absolute maximum dose rules. Critically, if a required parameter such as patient weight is missing, the function blocks the order rather than silently passing it.

The calculateNEWS2 function computes the National Early Warning Score 2 from seven vital sign inputs per Royal College of Physicians specification, returning total score, risk category, and escalation guidance such as urgent ICU review.

Alerts are classified as Critical, Major, or Minor. Critical alerts render as non-dismissable blocking modals requiring a documented override reason; Major alerts require acknowledgement; Minor alerts are informational only. Override reasons are stored in the audit trail.

Includes a ready-made test suite structure that enforces 100% pass rate across all interaction pairs (including reverse-direction), missing-parameter blocking, and graceful handling of malformed input. A single missed interaction is treated as a patient safety event.

Explicit documentation of dangerous implementation mistakes — including optional safety checks, toast-based critical alerts, silent error catching, and skipping weight validation — helps teams avoid common CDSS pitfalls that create patient risk.

Intercept dangerous drug-drug interactions and dose violations at the point of prescribing, blocking submission until the clinician documents an override reason or corrects the order.

Automatically compute NEWS2 scores from charted vital signs and surface high-risk results with escalation guidance, enabling timely clinical review for deteriorating patients.

Flag drugs that are cross-reactive with a patient's documented allergies as critical-severity alerts, preventing accidental administration of contraindicated medications.

Enforce reduced dose caps for patients with impaired renal function or paediatric age brackets, blocking orders that exceed adjusted maximums and suggesting safe dose ranges.